ViewSizerTM 3000
 Download ViewSizerTM 3000 Brochure
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The ViewSizerTM 3000 is an instrument that visualises scattering from individual nanoparticles in suspension. This data is used to determine particle movement and infer particle size using the Stokes Einstein Relationship. Then, by using the known illuminated and imaged sample volume, particle number concentration is readily determined. Thus, from a single measurement, two critical pieces of information are determined: Particle size distribution and particle concentration.
By incorporating three variable light sources (blue, green and red), the The ViewSizer 3000 is able to select the optimum conditions for any sample analysis, overcoming the limitations of NTA when analysing polydisperse sample and enabling a much larger range of particle sizes to be visualized. |
By introducing the sample in an easy-to-use (and clean) cuvette, the ViewSizer 3000 is able to repeatedly "analyze and stir", giving a much more reproducible result. And because the sample is viewed in a vertical orientation, it is perfect for visualising processes such as protein aggregation or crystal dissolution.
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Whether you are using NTA for the analysis of exosomes or other microvesicles or for complex nanoparticle kinetic processes, the ViewSizer 3000 is a breakthrough technology, bringing better analysis to your laboratory.
Whether you are using NTA for the analysis of exosomes or other microvesicles or for complex nanoparticle kinetic processes, the ViewSizer 3000 is a breakthrough technology, bringing better analysis to your laboratory.
Key Features
- High resolution particle size distribution and visualisation
- Wide range of particle sizes in the same sample
- Multiple light sources (blue, green and red)
- Perfect for monitoring nanoparticle kinetics
Instrument Specifications
| Measurement Range | 10 nm to 15 µm |
| Typical Sample Volume | 350 µL to 2.5 mL |
| Typical Sample Concentration (Sample dependent) | 10^5 - 10^9 particles/mL |
| Sample Temperature Range (Controlled) | 10° C to 50° C +/- 0.1° C |
| Dimensions | 55 cm W x 66 cm D x 35 cm H |
| Weight | 27 kg |
| Operational Environment | 15° C to 30° C with < 85% RH |
Particle Tracking Standards
Well accepted data can't be obtained without international standards. Dr Koltsov is leading the development and revision of the NTA/PTA ISO standards (ISO 19430) since 2013. The new version of the document allows for particle sizing, particle size distribution and particle counting that leads to particle number concnetration. 3-Laser systems, as well as the gravitational fall sizing are documented. It should also be noted that E2834-12(2022) is also used. Why is this importnat? This means that a certified lab operating under ISO 17025 can offer certified measurement reports.
Applications Notes
Videos and Tutorials
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Multi-laser Nanoparticle Tracking Analysis (NTA) is an advanced patented technology featuring three simultaneously operating lasers with independently adjustable power. This enables broad size distributions of, for example, biologics particle mixtures to be accurately analyzed for size and concentration. This webinar offers a broad overview on how multi-laser NTA technique fits into the gene therapy space and where we and our collaborators see the applications going in the near future. |
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In this webinar, Dr. Pushpendra Singh, of Walter Reed Army Institute of Research, discusses the significance of liposome size characteristics in medicine, including the challenges present in particle size measurement for heterogeneous size containing formulation (polydisperse). He will also discuss his recently published results on polydisperse bead and liposome formulations using DLS, conventional Nanoparticle Tracking Analysis (NTA), laser diffraction and a novel multispectral NTA measurement techniques. |
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Accurate concentration for virus and virus-like particles can be determined by multi-laser nanoparticle tracking analysis due to the fact they are nanoparticles. Other biologically relevant materials will have sizes that are close to those of viruses, whether they are protein aggregates that provoke an unwanted immune response or exosomes with a similar size and do not provoke an immune response |
Featured Publications for the ViewSizer 3000
These are the select publications relevant to or using ViewSizer 3000. This list will be updated periodically.
Contact your Distributor
Email: denis@brec-solutions.com
